The aim of the cruise was to collect by trawling a flatfish species, Solea solea, in the Golf of Gascogne. Sole is one of the sentinel species identified for South Europe for the biomonitoring of the marine environment (Cuevas et al., 2015). Collected samples will allow both chemical (tissue concentration of some organic and inorganic contaminants) and biological (measurement of condition index and biomarkers of both pollutant exposure and/or effects) analysis in the frame of the biomonitoring program of the Marine Water Framework Directive for descriptor 8: concentrations of contaminants give no effects.